Query: NC_016940:1698000 Saprospira grandis str. Lewin chromosome, complete genome Lineage: Saprospira grandis; Saprospira; Saprospiraceae; Sphingobacteriales; Bacteroidetes; Bacteria General Information: Gliding bacterium. Saprospira grandis is a gram-negative, marine, multicellular, filamentous flexibacterium. They prey on other bacteria by trapping and devouring them. It is significant because it is known for devouring bacteria and also has been shown to digest algae by the same process. This makes this bacterium important because it is useful in preventing harmful algal blooms. They are mesophilic with their optimum temperature being between 25-30 degrees C, and require a neutral pH. This filamentous organism is matile by gliding. This organism is able to lyse bacterial cells on the surfaces it is moving over.
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General Information: This strain is a standard laboratory strain. It is virulent for humans and cattle. Causes bovine brucellosis. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism was first noticed on the island of Malta. It is the primary cause of bovine brucellosis, which results in enormous (billions of dollars) economic losses due primarily to reproductive failure and food losses. In man, it causes undulant fever, a long debilitating disease that is treated by protracted administration of antibiotics.