Query: NC_016929:851044 Rickettsia canadensis str. CA410 chromosome, complete genome
Lineage: Rickettsia canadensis; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria
General Information: Members of this genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens. In both groups, the bacteria are transmitted via an insect, usually a tick, to a host organism where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. This organism was originally thought to be a member of the typhus group of Rickettsiales, however, it is now thought to represent a distict group with the rickettsia.
Subject: NC_010645:3720501 Bordetella avium 197N, complete genome
Lineage: Bordetella avium; Bordetella; Alcaligenaceae; Burkholderiales; Proteobacteria; Bacteria
General Information: This strain is a spontaneous nalidixic acid-resistant derivative of virulent strain 197. This group of organisms is capable of invading the respiratory tract of animals and causing severe diseases. They express a number of virulence factors in order to do this including filamentous hemagglutins for attachment, cytotoxins, and proteins that form a type III secretion system for transport of effector molecules into host cells. This organism infects the respiratory tract of birds, and causes bordetellosis in commercially important animals such as turkeys, resulting in devastating losses every year due to secondary infections.