Query: NC_016929:141972 Rickettsia canadensis str. CA410 chromosome, complete genome Lineage: Rickettsia canadensis; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria General Information: Members of this genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens. In both groups, the bacteria are transmitted via an insect, usually a tick, to a host organism where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. This organism was originally thought to be a member of the typhus group of Rickettsiales, however, it is now thought to represent a distict group with the rickettsia.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: Isolation: Patient with rat-bite fever in France; Temp: Mesophile; Temp: 37C; Habitat: Host. Streptobacillus moniliformis causes rat bite fever, a systemic illness characterized by fever, chills, and joint pain which can progress to endocarditis, meningitis or pneumonia if left untreated. Although infection is usually associated with a rodent bite, this disease can be caused by ingestion of contaminated food or water. Streptobacillus moniliformis is the causative agent of rat bite fever in North and South America while a different organism, Spirillum minus, is primarily responsible for this disease in Asia and other countries.