Pre_GI: SWBIT SVG BLASTN

Query: NC_016894:3329562 Acetobacterium woodii DSM 1030 chromosome, complete genome

Lineage: Acetobacterium woodii; Acetobacterium; Eubacteriaceae; Clostridiales; Firmicutes; Bacteria

General Information: Acetobacterium woodii is a Gram positive, motile, strict anaerobic, acetogenic bacterium, that relies on Na+ as coupling ion in bioenergetic reactions. The organism can use a wide range of substrates, such as sugars, alcohols, methoxylated aromatic acids or C1 compounds. Electrons derived from these electron donors are used in the Wood-Ljungdahl-pathway where the organism fixes CO2 and produces acetate. The pathway of CO2-fixation is coupled to energy conservation via a chemiosmotic mechanism, one enzyme that seems to be involved is the Rnf complex. The produced Na+ gradient can be used to drive ATP-synthesis or flagella rotation. The ATP synthase is a member of the F1FO class of enzymes and has an unusual hybrid rotor. Can use alternative electron acceptors like the lignin degradation product caffeate.

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BLASTN Alignment.txt

Subject: NC_007929:1805000 Lactobacillus salivarius subsp. salivarius UCC118, complete genome

Lineage: Lactobacillus salivarius; Lactobacillus; Lactobacillaceae; Lactobacillales; Firmicutes; Bacteria

General Information: Lactobacillus salivarius salivarius strain UCC118 was isolated from the human gastrointestinal tract. This organism produces bacteriocins, antibiotic compounds which have inhibitory effects on pathogenic microorganisms. Lactobacillus salivarius subsp. salivarius strain UCC118 has been extensively studied for its effectiveness as a probiotic to maintain the balance of the gut microbial flora and stimulate the intestinal immune system. Oral and gastrointestinal tract bacterium. They are commonly found in the oral, vaginal, and intestinal regions of many animals. They are important industrial microbes that contribute to the production of cheese, yogurt, and other products such as fermented milks, all stemming from the production of lactic acid, which inhibits the growth of other organisms as well as lowering the pH of the food product. Industrial production requires the use of starter cultures, which are carefully cultivated, created, and maintained, which produce specific end products during fermentation that impart flavor to the final product, as well as contributing important metabolic reactions, such as the breakdown of milk proteins during cheese production. The end product of fermentation, lactic acid, is also being used as a starter molecule for complex organic molecule syntheses. Lactobacillus salivarius was first isolated as part of a survey of human oral lactobacilli and is commonly found in the oral cavity and gastrointestinal tract of humans and other animals.