Query: NC_016887:5295120 Nocardia cyriacigeorgica GUH-2, complete genome Lineage: Nocardia cyriacigeorgica; Nocardia; Nocardiaceae; Actinomycetales; Actinobacteria; Bacteria General Information: Isolated from a fatal human nocardiosis case at Washington DC, USA in the 1970s. Human pathogen. Nocardia cyriacigeorgica is a filamentous actinobacteria, frequently isolated from diseased human and animal tissues. N. cyriacigeorgica is the most prevalent species responsible for nocardiosis in North America, while placing fourth in France.
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General Information: Rhodococcus erythropolis PR4 (NBRC 100887) was isolated from Pacific Ocean seawater. It has the enzymes necessary for the degradation of different alkanes, such as pristane. PR4 shows tolerance to hydrocarbons and it is capable of producing several compounds with medical, industrial, and nutritional applications such as beta-carotenes (i.e. astaxanthin) and fatty acid-containing extracellular polysaccharides (i.e. mucoidan). Rhodococcus species are soil bacteria with remarkable metabolic versatility leading to several possible applications in the pharmaceutical and chemical industries and for industrial bioremediation. This species has shown potential in producing different valuable compounds. As examples, some Rhodococcus erythropolis strains posses a nitrile hydratase, an enzyme used for the industrial production of acrylamide and nicotinamide, while other strains are capable of transforming indene to 1,2-indandiol, a key precursor of the AIDS drug Crixivan.