Query: NC_016884:157894 Sulfobacillus acidophilus DSM 10332 chromosome, complete genome
Lineage: Sulfobacillus acidophilus; Sulfobacillus; Clostridiales Family XVII; Clostridiales; Firmicutes; Bacteria
General Information: Country: United Kingdom; Environment: Soil; Isolation: coal spoil heap; Temp: Thermophile; Temp: 45C. Sulfobacillus acidophilus was first isolated from a coal spoil heap in the United Kingdom. This orgainism is an acidophilic sulfur- and iron-oxidizing bacterium capable of autotrophic growth on iron and sulfur.
Subject: NC_010263:278463 Rickettsia rickettsii str. Iowa, complete genome
Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria
General Information: Causative agent for Rocky Mountain Spotted Fever. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.