Pre_GI: SWBIT SVG BLASTN

Query: NC_016843:1 Treponema pallidum subsp. pertenue str. Gauthier chromosome,

Lineage: Treponema pallidum; Treponema; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: This strain was isolated in Brazzaville, the Republic of Congo in 1960. Treponema pallidum subsp. pertenue causes chronic and disfiguring illness called yaws. The disease starts as a skin infection causing persistent ulcers and progresses to form tumor-like masses. This disease tends to infect children and is common in rural areas in Africa, Southeast Asia and equatorial South America.

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BLASTN Alignment.txt

Subject: NC_000919:12545 Treponema pallidum subsp. pallidum str. Nichols, complete genome

Lineage: Treponema pallidum; Treponema; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: This strain was originally isolated in 1912 from a neurosyphilitic patient and is virulent. This organism is the causative agent of endemic and venereal syphilis. This sexual transmitted disease was first discovered in Europe at the end of the fifteenth century, however, the causative agent was not identified until 1905. At one time syphilis was the third most commonly reported communicable disease in the USA. Syphilis is characterized by multiple clinical stages and long periods of latent, asymptomatic infection. Although effective therapies have been available since the introduction of penicillin, syphilis remains a global health problem. This organisms is divided into subspecies each of which causes a specific disease. T. pallidum causes the venereal disease syphilis. T. pertenue, T. carateum and T. endemicum cause the skin infections yaws, pinta and bejel, respectively.