Pre_GI: SWBIT SVG BLASTN

Query: NC_016842:748419 Treponema pallidum subsp. pertenue str. SamoaD chromosome, complete

Lineage: Treponema pallidum; Treponema; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: This strain was isolated in Western Samoa in 1953. Treponema pallidum subsp. pertenue causes the chronic and disfiguring illness called yaws. The disease starts as a skin infection causing persistent ulcers and progresses to form tumor-like masses. This disease tends to infect children and is common in rural areas in Africa, Southeast Asia and equatorial South America.

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BLASTN Alignment.txt

Subject: NC_010677:353839 Francisella tularensis subsp. mediasiatica FSC147, complete genome

Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria

General Information: This isolate was collected from a gerbil in central Asia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.