Pre_GI: SWBIT SVG BLASTN

Query: NC_016822:3065426 Shigella sonnei 53G, complete genome

Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.

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BLASTN Alignment.txt

Subject: NC_003296:673790 Ralstonia solanacearum GMI1000 plasmid pGMI1000MP, complete

Lineage: Ralstonia solanacearum; Ralstonia; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria

General Information: This strain is a race 1 strain isolated from the tomato plant and is also pathogenic on Arabidopsis thaliana. It specifically invades the plant xylem. Plant pathogen. This organism is a phytopathogen that is found in the soil and causes systemic wilting disease in many important food crops such as tomatoes, potatoes, bananas, tobacco, pepper, peanut, ginger, and eucalyptus. It can infect plants found in over 50 different families and this pathogen can be carried asymptomatically in some species.