Pre_GI: SWBIT SVG BLASTN

Query: NC_016751:857359 Marinitoga piezophila KA3 chromosome, complete genome

Lineage: Marinitoga piezophila; Marinitoga; Thermotogaceae; Thermotogales; Thermotogae; Bacteria

General Information: Country: Pacific Ocean; Environment: Deep sea, Hydrothermal vent, Marine; Isolation: deep-sea hydrothermal vent chimney; Temp: Thermophile; Temp: 65C. Marinitoga piezophila was isolated from a deep-sea hydrothermal vent chimney at a depth of 2630 meters on the East-Pacific Rise. This organism grows best at a pressure of 40 MPa. This organism is a member of the Thermatogales and has the characteristic morphology of one or more cells contained in a sheath-like envelope which extends beyond the cell wall.

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Subject: NC_007799:968499 Ehrlichia chaffeensis str. Arkansas, complete genome

Lineage: Ehrlichia chaffeensis; Ehrlichia; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain is the first isolate of Ehrlichia chaffeensis, which was obtained from a patient on an army base in Arkansas, USA in 1990. Causes disease in humans. This organism is an obligate intracellular pathogen that exists within vacuoles in the cytoplasm of monocytes or granulocytes. Transferred during an insect (tick) bite, it can cause disease in humans (human monocytic ehrlichiosis) and can reside in several other animals and is a problem in immunocompromised patients. The bacterium inhibits phagosome-lysozome fusion as well as programmed cell death (apoptosis) of the host cell, similar to what is observed with Anaplasma phagocytophilum.