Query: NC_016749:1371997 Streptococcus macedonicus ACA-DC 198, complete genome Lineage: Streptococcus macedonicus; Streptococcus; Streptococcaceae; Lactobacillales; Firmicutes; Bacteria General Information: Streptococcus macedonicus (strain ACA-DC 198) is a thermophilic, homofermentative, Gram-positive bacterium isolated from a naturally fermented Greek Kasseri cheese. It possesses a food-grade and non-pathogenic status. S.macedonicus are moderately acidifying and proteolytic, and produce bacteriocins as the anti-clostridial lantibiotic macedocin.
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General Information: This strain is a serotype V clinical isolate and is the most common type amoung GBS-infected (group B streptococcal) non-pregnant adults. Causes meningitis and sepsis in newborns. Streptococci are Gram-positive, nonmotile, nonsporeforming, catalase-negative cocci that occur in pairs or chains. Members of this genus vary widely in pathogenic potential. Most streptococci are facultative anaerobes, and some are obligate anaerobes. Serologic grouping is based on antigenic differences in cell wall carbohydrates, in cell wall pili-associated protein, and in the polysaccharide capsule in group B streptococci. This organism is the leading cause of meningitis and sepsis in newborns. Additionally this organism is the cause of serious infections in immunocompromised adults. Able to asymptomatically colonize human skin and mucous membranes. This organism is also implicated in cases of mastitis in cows.