Query: NC_016745:2229271 Oceanimonas sp. GK1 chromosome, complete genome Lineage: Oceanimonas; Oceanimonas; Aeromonadaceae; Aeromonadales; Proteobacteria; Bacteria General Information: Oceanimonas sp. (strain GK1) is an aerobic, marine halotolerant, Gram-negative bacterium isolated from Gavkhouni Wetland in Iran. It is a motile bacterium which can tolerate up to 12% NaCl. It grows at tempatures between 10 to 45 degrees C with an optimum at 35 degrees C and at pH between 6 to 10 with an optimum at 8. Oceanimonas sp. produces large amounts of poly-hydroxybutyrate (PHB) as a carbon and energy reservoir under unbalanced growth conditions. PHB is a biodegradable and renewable biosynthetic polymer which can be used in medicine, tissue engineering, and packaging materials.
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General Information: Causes Q-fever. This organism is widely distributed in nature and can cause infections in reptiles, birds, and mammals. It causes Q fever, or 'query' fever, an atypical pneumonia first associated with abattoir workers in Australia. Transmission may be through insect vectors such as ticks that have bitten an infected wild or domesticated animal, or through an aerosol produced by domesticated animals such as sheep or cattle. The presence of a plasmid is believed to be associated with virulence and pathogenicity, however C. burnetii isolates containing plasmid QpDG are avirulent in guinea pigs and plasmidless isolates have been associated with endocarditis in humans. Coxiella burnetii has a developmental life cycle, and can grow vegetatively through binary fission, or asymmetrically and produce a spore-like cell. The spore-like cell may enable the organism to exist extracellularly for small amounts of time. This bacterium is an obligate intracellular pathogen. It is endocytosed by a host cell, a macrophage for example, and lives and replicates inside the phagolysozome, a unique property of this organism. The genome encodes proteins that have a higher than average pI, which may enable adaptation to the acidic environment of the phagolysozome. The chromosome also contains genes for a number of detoxification and stress response proteins such as dismutases that allow growth in the oxidative environment. The type IV system is similar to the one found in Legionella, which may be important for intracellular survival. This organism produces numerous ankyrin-repeat proteins that may be involved in interactions with the host cell. The genome has 83 pseudogenes, which may be a result of the typical genome-wide degradation observed with other intracellular organisms and also has a group I intron in the 23S ribosomal RNA gene.