Query: NC_016630:1385719 Filifactor alocis ATCC 35896 chromosome, complete genome Lineage: Filifactor alocis; Filifactor; Peptostreptococcaceae; Clostridiales; Firmicutes; Bacteria General Information: Filifactor alocis, originally known as Fusobacterium alocis, was first isolated in1985 from the human gingival crevice, and has since been discovered in patients suffering from chronic periodontitis, generalized aggressive, periodontitis and endodontic infections. It has also been isolated from feline soft tissue infections. It is a fastidious, Gram-positive obligately anaerobic rod. Bacteria in periodontal pockets develop complex sessile communities that attach to the tooth surface.
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General Information: This strain is a spontaneous nalidixic acid-resistant derivative of virulent strain 197. This group of organisms is capable of invading the respiratory tract of animals and causing severe diseases. They express a number of virulence factors in order to do this including filamentous hemagglutins for attachment, cytotoxins, and proteins that form a type III secretion system for transport of effector molecules into host cells. This organism infects the respiratory tract of birds, and causes bordetellosis in commercially important animals such as turkeys, resulting in devastating losses every year due to secondary infections.