Query: NC_016630:1385719 Filifactor alocis ATCC 35896 chromosome, complete genome Lineage: Filifactor alocis; Filifactor; Peptostreptococcaceae; Clostridiales; Firmicutes; Bacteria General Information: Filifactor alocis, originally known as Fusobacterium alocis, was first isolated in1985 from the human gingival crevice, and has since been discovered in patients suffering from chronic periodontitis, generalized aggressive, periodontitis and endodontic infections. It has also been isolated from feline soft tissue infections. It is a fastidious, Gram-positive obligately anaerobic rod. Bacteria in periodontal pockets develop complex sessile communities that attach to the tooth surface.
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General Information: This strain was isolated in 1989 in North Carolina, USA from a 2-year-old male dog. This organisms causes canine monocytic ehrlichiosis, which is a tick-born disease that causes severe morbidity in domesticated and wild dogs. The brown dog tick, Rhipicephalus sanguineus, transfers the organism from its salivary glands to the animal when feeding. Persistence in the vacuole leads to replication and cell division and eventual release from the cell which leads to further spreading of the bacterium throughout the host. The end result is an increase in platelet count and anemia.