Query: NC_016513:1761830 Aggregatibacter actinomycetemcomitans ANH9381 chromosome, complete
Lineage: Aggregatibacter actinomycetemcomitans; Aggregatibacter; Pasteurellaceae; Pasteurellales; Proteobacteria; Bacteria
General Information: Aggregatibacter actinomycetemcomitans, previously Actinobacillus actinomycetemcomitans typically resides in the oral cavity of humans and animals and can cause a number of diseases. The bacterium, along with 3 other organisms, is the main culprit in periodontis, which results in devastation to the bone supporting the teeth. Adherence to oral surfaces is controlled through the tad (tight adherence) locus, which may express proteins that are involved in type IV secretion.
Subject: NC_012225:2523262 Brachyspira hyodysenteriae WA1, complete genome
Lineage: Brachyspira hyodysenteriae; Brachyspira; Brachyspiraceae; Spirochaetales; Spirochaetes; Bacteria
General Information: Brachyspira hyodysenteriae is the causative agent of swine dysentery, which is a severe mucohemorrhagic diarrheal disease of pigs that has economic significance for pork-producing countries. The bacterium can survive for several weeks in cold moist conditions but not under warm dry conditions. It spreads slowly, building up in numbers as the dose rate of the causal agent builds up in the environment. Pigs that recover develop a low immunity and rarely suffer from the disease again. It can be spread by other organisms (flies, mice, birds and dogs) or external mechanical factors; its main habitat is the porcine cecum and colon. It is chemotactically attracted to mucin which it penetrates with a corkscrew-like motility.