Query: NC_016112:3840053 Methylomicrobium alcaliphilum chromosome, complete genome
Lineage: Methylomicrobium alcaliphilum; Methylomicrobium; Methylococcaceae; Methylococcales; Proteobacteria; Bacteria
General Information: Methanotroph, Ammonia oxidation, Thiosulfate oxidation. Haloalkaliphilic methanotrophic bacterium. Halotolerant, alkaliphilic, obligate methanotrophic, Gram-negative bacterium isolated from moderately saline soda lakes in Tuva (Central Asia)
Subject: NC_003112:149593 Neisseria meningitidis MC58, complete genome
Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria
General Information: The B serogroup is responsible for many of the meningitis outbreaks in the developed world. This strain was isolated from a case of invasive infection. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.