Query: NC_015930:1397524 Lactococcus garvieae ATCC 49156, complete genome
Lineage: Lactococcus garvieae; Lactococcus; Streptococcaceae; Lactobacillales; Firmicutes; Bacteria
General Information: Lactococcus garviae is responsible for mastitis in cows and buffalos, and it has been isolated from clinical specimens of human blood, urine, and skin. Lactococcus garvieae is also a well recognized bacterial fish pathogen. L. garvieae as the etiological agent of a hemorrhagic septicemia in farmed trout that was characterized by bilateral exophthalmos, darkening of the skin, congestion of the intestine, liver, kidney, spleen, and brain.
Subject: NC_008710:621822 Borrelia turicatae 91E135, complete genome
Lineage: Borrelia turicatae; Borrelia; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria
General Information: This strain was isolated in the USA from the soft tick Ornithodoros turicatae. Borrelia turicatae is the causative agent of tick-borne relapsing fever in the southwestern USA. Ticks become infected with Borrelia while feeding on an infected mammal, usually a rodent or squirrel. Borrelia then multiplies rapidly, causing a generalized infection throughout the tick. While feeding, the tick passes the spirochete into a mammalian host through its infectious saliva. Relapsing fever is characterized by period of chills, fever, headache, and malaise, followed by an asymptomatic, followed by another episode of symptoms. The cycle of relapsing is due to changes in the surface proteins of Borrelia, which allow it to avoid detection and removal by the host immune system. This antigenic variation is the result of homologous recombination of silent proteins into an expressed locus, causing partial or complete replacement of one serotype with another. These plasmids carry genes involved in antigenic variation and pathogenicity.