Query: NC_015914:3197772 Cyclobacterium marinum DSM 745 chromosome, complete genome
Lineage: Cyclobacterium marinum; Cyclobacterium; Cyclobacteriaceae; Cytophagales; Bacteroidetes; Bacteria
General Information: Isolation: Coelomic fluid of a sand dollar; Temp: Mesophile. Gram-negative bacterium isolated from coelomic fluid of a sand dollarfish (Poronotus triacanthus) of the family Stromateidae (butterfish family), a family of fishes with almost circular bodies and small mouths. The dollarfish (genus Peprilus), is found from Maine to South Carolina, USA during the summer.
Subject: NC_008710:79100 Borrelia turicatae 91E135, complete genome
Lineage: Borrelia turicatae; Borrelia; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria
General Information: This strain was isolated in the USA from the soft tick Ornithodoros turicatae. Borrelia turicatae is the causative agent of tick-borne relapsing fever in the southwestern USA. Ticks become infected with Borrelia while feeding on an infected mammal, usually a rodent or squirrel. Borrelia then multiplies rapidly, causing a generalized infection throughout the tick. While feeding, the tick passes the spirochete into a mammalian host through its infectious saliva. Relapsing fever is characterized by period of chills, fever, headache, and malaise, followed by an asymptomatic, followed by another episode of symptoms. The cycle of relapsing is due to changes in the surface proteins of Borrelia, which allow it to avoid detection and removal by the host immune system. This antigenic variation is the result of homologous recombination of silent proteins into an expressed locus, causing partial or complete replacement of one serotype with another. These plasmids carry genes involved in antigenic variation and pathogenicity.