Query: NC_015858:1150446 Brucella pinnipedialis B2/94 chromosome chromosome 2, complete
Lineage: Brucella pinnipedialis; Brucella; Brucellaceae; Rhizobiales; Proteobacteria; Bacteria
General Information: Brucella pinnipedialis has been isolated from seals, porpoises and other marine mammals. This organism can be isolated from skin, blood, spleen and lymph nodes although the pathogenesis of this organism has yet to be determined.
Subject: NC_007880:1703346 Francisella tularensis subsp. holarctica, complete genome
Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria
General Information: This strain (live vaccine strain) was created in the 1960's in the USA and provides protection against tularemia in animal models as well as in humans. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.