Pre_GI: SWBIT SVG BLASTN

Query: NC_015760:8914 Streptococcus salivarius CCHSS3, complete genome

Lineage: Streptococcus salivarius; Streptococcus; Streptococcaceae; Lactobacillales; Firmicutes; Bacteria

General Information: The commensal bacterium Streptococcus salivarius is predominant specie of the human oropharyngeal tract and exerts an important role in oral ecology. Streptococcus salivarius is an aerobic, gram-positive coccus. This organism is the most common organism isolated from the human oral cavity. Streptococcus salivarius can also be an opportunistic pathogen causing endocarditis, blood infection, and peritonitis. Streptococci are Gram-positive, nonmotile, nonsporeforming, catalase-negative cocci that occur in pairs or chains. Members of this genus vary widely in pathogenic potential. Most streptococci are facultative anaerobes, and some are obligate anaerobes.

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Subject: NC_014802:716699 Campylobacter jejuni subsp. jejuni ICDCCJ07001 chromosome, complete

Lineage: Campylobacter jejuni; Campylobacter; Campylobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: Gram-negative, microaerophilic, flagellate, spiral bacterium, Campylobacter species are the leading cause of food-borne gastroenteritis in developed countries. Infection with C. jejuni is the most frequent antecedent to a form of neuromuscular paralysis known as Guillain-Barre syndrome (GBS). Strain ICDCCJ07001 was isolated following a GBS outbreak in Shuangyang, a town in northern China in 2007, from a severely affected 15 year-old girl GBS patient who had been on a ventilator for 180 days. Her clinical symptoms were motor axonal neuropathy. This organism is the leading cause of bacterial food poisoning (campylobacteriosis) in the world, and is more prevalent than Salmonella enteritis (salmonellosis). Found throughout nature, it can colonize the intestines of both mammals and birds, and transmission to humans occurs via contaminated food products. This organism can invade the epithelial layer by first attaching to epithelial cells, then penetrating through them. Systemic infections can also occur causing more severe illnesses.