Pre_GI: SWBIT SVG BLASTN

Query: NC_015703:4933430 Runella slithyformis DSM 19594 chromosome, complete genome

Lineage: Runella slithyformis; Runella; Cytophagaceae; Cytophagales; Bacteroidetes; Bacteria

General Information: Environment: Fresh water, Host; Isolation: Fresh water lake; USA, Louisiana, Baton; Temp: Psychrophile. This is a species of curved, nonflexible, pink bacteria. The species is of interest because it is able to grow at temperatures as low as 4°C. The species epithet is derived from slithy, a nonsense word from Lewis Carroll's Jabberwocky for a fictional organism that is 'slithy' and the Latin word 'suffix' meaning '-like, in the shape of', yielding the Neo-Latin word 'slithyformis' meaning 'slithy in form'.

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BLASTN Alignment.txt

Subject: NC_004668:241352 Enterococcus faecalis V583, complete genome

Lineage: Enterococcus faecalis; Enterococcus; Enterococcaceae; Lactobacillales; Firmicutes; Bacteria

General Information: This strain is one of the first vancomycin-resistant strains isolated. This isolate came from a blood culture derived from a chronically-infected patient in 1987 from Barnes Hospital in St. Louis, Missouri, USA. This strain was found to lack the cytolysin gene and a surface adhesin, Esp, that contributes to urinary tract infections. Mobile genetic elements make up one quarter of the genome. This genera consists of organisms typically found in the intestines of mammals, although through fecal contamination they can appear in sewage, soil, and water. They cause a number of infections that are becoming increasingly a problem due to the number of antibiotic resistance mechanisms these organisms have picked up. Both Enterococcus faecalis and Enterococcus faecium cause similar diseases in humans, and are mainly distinguished by their metabolic capabilities. This opportunistic pathogen can cause urinary tract infections, bacteremia (bacteria in the blood), and infective endocarditis (inflammation of the membrane surrounding the heart), similar to infections caused by Enterococcus faecium. Hospital-acquired infections from this organism are on the rise due to the emergence of antiobiotic resistance strains. Enterococcus faecalis produces a cytolysin toxin that is encoded on various mobile genetic elements, pathogenicity islands, and conjugative plasmids. The cytolysin aids in pathogenesis, possibly by causing destruction of cells such as erythrocytes, which allows access to new nutrients for the organism.