Query: NC_015687:303810 Clostridium acetobutylicum DSM 1731 chromosome, complete genome Lineage: Clostridium acetobutylicum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria General Information: This organism is a benign saccharolytic and proteolytic soil bacterium capable of producing a number of organic solvents (solventogenic bacterium) through fermentation of various organic compounds. The first strains of C. acetobutyricum were isolated by Chaim Weizman during the World War I and used to develop industrial starch-based acetone, butanol and ethanol fermentation processes.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: This strain was isolated from an infected goat and is pathogenic in humans. Causes brucellosis and undulant fever. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism is a facultative intracellular bacteria that causes abortion in wild and domestic animals, usually goats or sheep, and undulant fever in humans. Brucellosis is a major health problem in the Mediterranean region and parts of Asia, Africa, and Latin America, where it causes severe economic losses. The disease is transmitted to humans by nonpasteurized milk and milk products or by direct contact with infected animals or carcasses.