Query: NC_015683:2469481 Corynebacterium ulcerans BR-AD22 chromosome, complete genome
Lineage: Corynebacterium ulcerans; Corynebacterium; Corynebacteriaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: They may be found as members of the normal microflora of humans, where these bacteria find a suitable niche in virtually every anatomic site. Corynebacterium ulcerans is commonly associated with dairy animals and unpasturized dairy products. This organism has been implicated in bovine mastitis and can cause skin infections and a diptheria-like disease in humans.
Subject: NC_018870:1417851 Thermacetogenium phaeum DSM 12270 chromosome, complete genome
Lineage: Thermacetogenium phaeum; Thermacetogenium; Thermoanaerobacteraceae; Thermoanaerobacterales; Firmicutes; Bacteria
General Information: Nitrogen fixation. Thermophilic strictly anaerobic bacterium oxidizing acetate to CO2 in syntrophic association with a methanogenic partner. Capable of growing with various substrates such as alcohols and methylated nitrogen compounds, and to reduce sulfate in the presence of acetate. Isolated from sludge of an anaerobic digester run at 58 degrees C. Thermacetogenium phaeum is a strictly anaerobic, homoacetogenic bacterium. It is exceptional because it can use the homoacetogenic Wood-Ljungdahl (CO- dehydrogenase) pathway both for acetate formation and acetate oxidation. Acetate oxidation is possible only in syntrophic cooperation with a methanogenic partner which maintains a low hydrogen and/or formate concentration in the coculture. With this, the bacterium operates close to the thermodynamic equilibrium of substrate conversion, similar to other syntrophically fermenting bacteria such as Syntrophomonas wolfei the genomes of which have been sequenced as well in the recent past.