Query: NC_015678:1443178 Streptococcus parasanguinis ATCC 15912 chromosome, complete genome Lineage: Streptococcus parasanguinis; Streptococcus; Streptococcaceae; Lactobacillales; Firmicutes; Bacteria General Information: Most streptococci are facultative anaerobes, and some are obligate anaerobes. Serologic grouping is based on antigenic differences in cell wall carbohydrates, in cell wall pili-associated protein, and in the polysaccharide capsule in group B streptococci. This is a species of Gram-positive, non-motile, non-spore-forming, cocci. It has been isolated from human throat, blood and urine and from ovine clinical samples. It can cause subclinical mastitis in sheep and is involved in dental plaque formation in humans
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General Information: This strain was isolated from stool samples from an outbreak that involved three individuals in Nebraska, USA 1996. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.