Query: NC_015634:3017564 Bacillus coagulans 2-6 chromosome, complete genome Lineage: Bacillus coagulans; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria General Information: Bacillus coagulans, a lactic acid producing bacterium, was first identified as a spoilage agent of milk products. This organism can be used in the production of ethanol and lactic acid from cellulose and hemicellulose acid hydrolysate. Bacillus coagulans also produces other commercially important chemicals like cyclodextrins and amylases, and has been used as a probiotic in animal feed.
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General Information: Normal oral and gastrointestinal bacterium. This genus contains mostly obligately anaerobic bacilli. Many of the isolates are spindle-shaped, or fusiform. This organism belongs to the normal microflora of the human oral and gastrointestinal tracts. It is a very long and slender spindle-shaped bacillus with sharply pointed ends that is characterized by the ability to invade soft tissues. It acts as a bridge between early and late colonizers of the tooth surface, and exerts synergism with other bacteria in mixed infections. It is most frequently associated with periodontal diseases, as well as with some invasive human infections of the head and neck, chest, lung, liver and abdomen, and some anginas. One of the major amino acid and sugar fermentation pathways in Fusobacterium nucleatum produces butyric and acetic acids.