Pre_GI: SWBIT SVG BLASTN

Query: NC_015573:3070582 Desulfotomaculum kuznetsovii DSM 6115 chromosome, complete genome

Lineage: Desulfotomaculum kuznetsovii; Desulfotomaculum; Peptococcaceae; Clostridiales; Firmicutes; Bacteria

General Information: Country: Georgia; Environment: Animal intestinal microflora, Fresh water; Isolation: underground thermal mineral water; Temp: Mesophile; Temp: 60C. Desulfotomaculum kuznetsovii is a thermophilic spore-forming bacterium which can grow using sulfate as an electron acceptor. This organism is isolate from hot springs and oil field samples.

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Subject: NC_007880:1667922 Francisella tularensis subsp. holarctica, complete genome

Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria

General Information: This strain (live vaccine strain) was created in the 1960's in the USA and provides protection against tularemia in animal models as well as in humans. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.