Pre_GI: SWBIT SVG BLASTN

Query: NC_015500:2866027 Treponema brennaborense DSM 12168 chromosome, complete genome

Lineage: Treponema brennaborense; Treponema; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: Environment: Host; Isolation: Ulcerative lesion of a bovine foot infected; Temp. Mesophile. This organism is the causative agent for digital dermatitis in bovines. This disease produces painful lesions on the foot and can cause weight loss and decreased milk production.

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Subject: NC_013316:1 Clostridium difficile R20291, complete genome

Lineage: Peptoclostridium difficile; Peptoclostridium; Peptostreptococcaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium difficile R20291 was isolated in Stoke Mandeville Hospital, UK in 2006 and is closely related to the North American hypervirulent BI strains. Clostridium difficile, a Gram-positive, spore-forming anaerobic bacterium, is the leading cause of infectious diarrhea among patients in hospitals worldwide, causing C. difficile infection (CDI). An important nosocomial pathogen, it is frequently associated with antibiotic treatment and causes diseases ranging from antibiotic-associated diarrhea to life-threatening pseudomembraneous colitis.