Query: NC_015424:1689500 Aeromonas veronii B565 chromosome, complete genome
Lineage: Aeromonas veronii; Aeromonas; Aeromonadaceae; Aeromonadales; Proteobacteria; Bacteria
General Information: Aeromonas veronii is a Gram-negative, rod-shaped bacterium found in fresh water and in association with animals. It can be a pathogen of humans and a beneficial symbiont of leeches. In humans A. veronii can cause diseases ranging from wound infections and diarrhea to septicemia in immunocompromised patients. In leeches, this bacterium is thought to function in the digestion of blood, provision of nutrients or preventing other bacteria from growing.
Subject: NC_010120:609323 Neisseria meningitidis 053442, complete genome
Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria
General Information: Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.