Query: NC_015186:1504275 Acidiphilium multivorum AIU301, complete genome Lineage: Acidiphilium multivorum; Acidiphilium; Acetobacteraceae; Rhodospirillales; Proteobacteria; Bacteria General Information: Thiosulfate oxidation. Acidophilic, aerobic, anoxygenic, phototrophic, Gram-negative bacterium isolated from pyritic acid mine drainage. A.multivorum has high ability of resistance to various metals under acidic condition, and require high acidity for growth. It exhibits tolerance towards some heavy metal ions like nickel, zinc, cadmium and copper, and resistance to arsenate and arsenite.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.