Pre_GI: SWBIT SVG BLASTN

Query: NC_015152:1230995 Spirochaeta sp. Buddy chromosome, complete genome

Lineage: Sphaerochaeta globosa; Sphaerochaeta; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: Country: Russia; Environment: Hot spring, Marine; Isolation: Marine hot spring; USSR, Shiashkoten island; Temp: Hyperthermophile; Temp: 65C. This is a genus of spirochetes with a flexible, undulating, spiral-shaped body.

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Subject: NC_008343:2589680 Granulibacter bethesdensis CGDNIH1, complete genome

Lineage: Granulibacter bethesdensis; Granulibacter; Acetobacteraceae; Rhodospirillales; Proteobacteria; Bacteria

General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.