Query: NC_014909:619407 Candidatus Blochmannia vafer str. BVAF chromosome, complete genome
Lineage: Blochmannia vafer; Blochmannia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria
General Information: Candidatus Blochmannia is an obligate bacterial associate of Camponotus and related ant genera. Blochmannia vafer was isolated from Camponotus vafer workers and larvae collected from a single colony in the Coronado National Forest near Portal, Arizona, USA. Blochmannia is located within bacteriocytes, where the bacterial cells float freely in the host cytoplasm, and within oocytes of queens.
Subject: NC_004917:340997 Helicobacter hepaticus ATCC 51449, complete genome
Lineage: Helicobacter hepaticus; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria
General Information: This organism was found to be linked to an increasing incidence of liver tumors in mouse colonies at the National Cancer Institute in 1992. Normally it resides in the lower intestines, but it can cause chronic hepatitis. This organism has a similar urease gene cluster and cytolethal distending toxin as compared to Helicobacter pylori, but lacks other virulence factors such as the vacuolating cytotoxin and the cag pathogenicity island. However, it does contain a pathogenicity island that encodes proteins similar to those found in a type IV secretion system. Causes liver disease. This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). This species was associated with an increase in liver tumors. It can cause active chronic hepatitis and typhlitis (inflammation of a region at the beginning of the large intestine), hepatocellular tumors, and gastric bowel disease in various mice strains.