Query: NC_014833:3667748 Ruminococcus albus 7 chromosome, complete genome Lineage: Ruminococcus albus; Ruminococcus; Ruminococcaceae; Clostridiales; Firmicutes; Bacteria General Information: Environment: Host; Temp: Mesophile; Temp: 40C. The bacterium requires phenylacetic and phenylpropionic acids for maximal growth. The organism produces cellulosomes at the cell surface that are multimeric protein complexes that contain scaffolding proteins and degradative enzymes. Understanding the metabolism of plant polysaccharides may enable scientists to improve the productivity of ruminant organisms such as cattle
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: This strain was isolated from human gingiva. This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.