Query: NC_014664:2373451 Rhodomicrobium vannielii ATCC 17100 chromosome, complete genome Lineage: Rhodomicrobium vannielii; Rhodomicrobium; Hyphomicrobiaceae; Rhizobiales; Proteobacteria; Bacteria General Information: Temp: Mesophile; Rhodomicrobium vannielii is a budding prosthecate bacterium. Rhodomicrobium vannielii is a purple non-sulfur bacterium isolated in 1949 that is photosynthetic under anaerobic conditions. It is able to grow with ferrous iron as electron donor, although this does not support growth over a long time.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: Bartonella henselae str. Houston-1 (ATCC 49882) was isolated from human blood in Houston Texas. Causative agent of cat scratch fever. This group of alpha proteobacteria are unique among pathogens in that they cause angiogenic lesions. This organism was identified as the causative agent of cat scratch fever, a disease found commonly in children or in immunocompromised adults. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells.