Query: NC_014654:2101500 Halanaerobium sp. 'sapolanicus' chromosome, complete genome
Lineage: Halanaerobium hydrogeniformans; Halanaerobium; Halanaerobiaceae; Halanaerobiales; Firmicutes; Bacteria
General Information: Environment: Fresh water, Sediment; Temp: Mesophile; Temp: 34 - 42C. Organisms identified in the genus Halanaerobium (also known as Haloanaerobium) were first isolated from the Great Salt Lake in Utah, USA and have since been isolated from diverse saline environments such as oil reserviors, brine-seawater interfaces and hypersaline sediments. These bacteria are extremely salt-tolerant and are able to grow in concentrations of salt as high as 25%.
Subject: NC_006142:140853 Rickettsia typhi str. Wilmington, complete genome
Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria
General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. Rickettsia typhi causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.