Query: NC_014641:20103 Achromobacter xylosoxidans A8 plasmid pA81, complete sequence Lineage: Achromobacter xylosoxidans; Achromobacter; Alcaligenaceae; Burkholderiales; Proteobacteria; Bacteria General Information: Achromobacter xylosoxidans strain A8 was isolated from soil contaminated with polychlorinated biphenyls (PCBs) and is able to use 2-chlorobenzoate (2-CB) and 2,5-dichlorobenzoate (2,5-DCB) as sole sources of carbon and energy. Achromobacter xylosoxidans is a catalase- and oxidase-positive, motile, gram-negative rod that can cause opportunistic infections in immunocompromised patients.
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General Information: This species is associated with infections in cystic fibrosis patients. It is an important opportunistic pathogen, colonizing the lungs and associated with a decrease in long-term survival. A minority of patients with this infection may also develop "cepacia syndrome", which leads to an acute clinical decline which is frequently fatal. This species is a member of the Burkholderia cepacia complex, although it does not appear to spread from patient to patient as do the other members of the group.