Query: NC_014614:6115 Clostridium sticklandii, complete genome Lineage: Clostridium sticklandii; Clostridium; unclassified Peptostreptococcaceae; Clostridiales; Firmicutes; Bacteria General Information: This Clostridium (HF strain, ATCC 12662) was initially found associated with Methanococcus vannieli in formate-enriched cultures. After its isolation in pure culture, it was shown that this organism is capable of fermenting amino acids. Biochemical studies have shown that C. sticklandii obtains energy for growth from oxidation-reduction reactions between specific amino acid pairs. Clostridium sticklandii is a Gram-positive bacterium with low (G +C) content that is capable of fermenting amino acids.
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General Information: This strain was isolated from a sample of coastal sea water near a French Antarctic station. This organism is adapted to growth at low temperatures and reactive oxygen species by a number of putative dioxygenases and fatty acid desaturases amongst other proteins. The organism can grow optimally in salt concentrations of 1.5 to 3.5% NaCl.The genome consists of 2 chromosomes, one of which may replicate unidirectionally. Some interesting features of this genome include the lack of the nucleoid-associated gene hns, a lack of genes involved in molybdopterin metabolism, a lack of the cAMP-CAP complex, and a lack of the PEP-dependent PTS system.