Query: NC_014471:1269571 Ignisphaera aggregans DSM 17230 chromosome, complete genome Lineage: Ignisphaera aggregans; Ignisphaera; Desulfurococcaceae; Desulfurococcales; Crenarchaeota; Archaea General Information: Country: New Zealand; Environment: Fresh water, Hot spring; Isolation: hot springs in Rotorua and Tokaanu, New Zealand; Temp: Hyperthermophile; Temp: 92C. Ignisphaera aggregans is a hyperthermophilic crenarchaeote isolated from hot springs in Rotorua and Tokaanu, New Zealand.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.