Query: NC_014448:9419 Mycoplasma hyorhinis HUB-1 chromosome, complete genome Lineage: Mycoplasma hyorhinis; Mycoplasma; Mycoplasmataceae; Mycoplasmatales; Tenericutes; Bacteria General Information: Mycoplasma hyorhinis HUB-1 was isolate from the respiratory tract of swine. Mycoplasma hyorhinis, though generally considered being a swine pathogen, is found most commonly infecting laboratory cell lines including human cells. Recently, an increasing body of work suggests that chronic infections of M. hyorhinis may cause oncogenic transformation. Infection with mycoplasma is a common problem in cell cultures, with Mycoplasma hyorhinis being the predominant species.
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General Information: This biovar nodulates legumes in the Tribe Viciae (Vicia, Pisum, Lathyrus, Lens). This strain is a spontaneous streptomycin-resistant mutant of strain 300. Nitrogen-fixing plant symbiont. This organism, like other Rhizobia, establishes a symbiotic relationship with a legume plant, providing nitrogen in exchange for a protected environment. The legume roots secrete flavonoids and isoflavonoids which the bacteria recognize and use to turn on genes involved in root nodulation. Many of the root nodulation genes are involved in synthesis and secretion of a nodule inducing signal, a lipochito-oligosaccharide molecule, which the plant recognizes, triggering nodule formation. The bacterium is endocytosed and exists inside a membrane bound organelle, the symbiosome, and fixes nitrogen for the plant cell while the host cell provides carbon compounds for the bacterium to grow on. The nitrogen fixation is important as it obviates the need for expensive and environmentally damaging fertilizer use.