Pre_GI: SWBIT SVG BLASTN

Query: NC_014392:2350577 Caldicellulosiruptor obsidiansis OB47 chromosome, complete genome

Lineage: Caldicellulosiruptor obsidiansis; Caldicellulosiruptor; Thermoanaerobacterales Family III; Thermoanaerobacterales; Firmicutes; Bacteria

General Information: Country: USA; Environment: Hot spring; Habitat: Fresh water, Hot spring; Isolation: Obsidian Pool, Yellowstone National Park, USA; Temp: 55-85C. This species is an extremely thermophilic anaerobic bacteria, isolated from Obsidian Pool, Yellowstone National Park. It is a novel cellulolytic bacteria. Caldicellulosiruptor is a genus of thermophilic gram positive bacteria. These organisms produce a number of thermostable enzymes which may have industrial uses.

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Subject: NC_007624:1046500 Brucella melitensis biovar Abortus 2308 chromosome II, complete

Lineage: Brucella abortus; Brucella; Brucellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: This strain is a standard laboratory strain. It is virulent for humans and cattle. Causes bovine brucellosis. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism was first noticed on the island of Malta. It is the primary cause of bovine brucellosis, which results in enormous (billions of dollars) economic losses due primarily to reproductive failure and food losses. In man, it causes undulant fever, a long debilitating disease that is treated by protracted administration of antibiotics.