Query: NC_014329:1298644 Corynebacterium pseudotuberculosis FRC41 chromosome, complete Lineage: Corynebacterium pseudotuberculosis; Corynebacterium; Corynebacteriaceae; Actinomycetales; Actinobacteria; Bacteria General Information: Strain FRC41 was isolated from the inguinal lymph node of a 12-year-old girl in France with necrotizing lymphadenitis. Corynebacterium pseudotuberculosis, an important animal pathogen, is the etiological agent of a disease that is commonly called caseous lymphadenitis (CLA) or cheesy gland. This disease is found in all the world's major sheep and goat production areas, causing significant economic losses worldwide, mainly due to the reduction of wool, meat and milk yields, decreased reproductive efficiencies of affected animals and condemnation of carcasses and skins in abattoirs. In some cases, the infection produces few obvious clinical signs in the animal, remaining unrecognized until a post-mortem examination has been carried out and, making it difficult to obtain definitive data about prevalence of the disease.
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General Information: Isolated from a case of meningitis. Causes opportunistic infections in hospitals. This bacterium is commonly isolated from the hospital environment and hospitalized patients. It is an aquatic organism, and is often cultured from liquid medical samples such as respiratory secretions, wounds, and urine. Acinetobacter also colonizes irrigating solutions and intravenous solutions. Although it has low virulence, it is capable of causing infection. Most isolates recovered from patients represent colonization rather than infection. When infections do occur, they usually occur in the blood, or in organs with a high fluid content, such as the lungs or urinary tract. Infections by this organism are becoming increasingly problematic due to the high number of resistance genes found in clinical isolates. Some strains are now resistant to all known antibiotics. Most of these genes appear to have been transferred horizontally from other organisms.