Pre_GI: SWBIT SVG BLASTN

Query: NC_014218:253558 Arcanobacterium haemolyticum DSM 20595 chromosome, complete genome

Lineage: Arcanobacterium haemolyticum; Arcanobacterium; Actinomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Temp: Mesophile; Temp: 37C; Habitat: Blood, Host. Non-motile, non-sporulating, rod-shaped facultative anaerobe. Arcanobacterium haemolyticum originally Corynebacterium was identified as the causative agent for pharyngitis in 1946. This organism has also been implicated in cases of sepsis, osteomyelitis and skin infections.

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Subject: NC_018870:484000 Thermacetogenium phaeum DSM 12270 chromosome, complete genome

Lineage: Thermacetogenium phaeum; Thermacetogenium; Thermoanaerobacteraceae; Thermoanaerobacterales; Firmicutes; Bacteria

General Information: Nitrogen fixation. Thermophilic strictly anaerobic bacterium oxidizing acetate to CO2 in syntrophic association with a methanogenic partner. Capable of growing with various substrates such as alcohols and methylated nitrogen compounds, and to reduce sulfate in the presence of acetate. Isolated from sludge of an anaerobic digester run at 58 degrees C. Thermacetogenium phaeum is a strictly anaerobic, homoacetogenic bacterium. It is exceptional because it can use the homoacetogenic Wood-Ljungdahl (CO- dehydrogenase) pathway both for acetate formation and acetate oxidation. Acetate oxidation is possible only in syntrophic cooperation with a methanogenic partner which maintains a low hydrogen and/or formate concentration in the coculture. With this, the bacterium operates close to the thermodynamic equilibrium of substrate conversion, similar to other syntrophically fermenting bacteria such as Syntrophomonas wolfei the genomes of which have been sequenced as well in the recent past.