Query: NC_014218:1948165 Arcanobacterium haemolyticum DSM 20595 chromosome, complete genome
Lineage: Arcanobacterium haemolyticum; Arcanobacterium; Actinomycetaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: Temp: Mesophile; Temp: 37C; Habitat: Blood, Host. Non-motile, non-sporulating, rod-shaped facultative anaerobe. Arcanobacterium haemolyticum originally Corynebacterium was identified as the causative agent for pharyngitis in 1946. This organism has also been implicated in cases of sepsis, osteomyelitis and skin infections.
Subject: NC_009142:827912 Saccharopolyspora erythraea NRRL 2338, complete genome
Lineage: Saccharopolyspora erythraea; Saccharopolyspora; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: Source of the antibiotic erythromycin. Saccharopolyspora erythraea is the soil bacterium that produces the industrially important antibiotic erythromycin A. Erythromycin is a clinically important and potent macrolide antibiotic. It is used to treat infections caused by several prokaryotic pathogens such as Streptococcus, Staphylococcus, Mycoplasma, Ureaplasma, Chlamydia and Legionella. Production of this antibiotic is lower than others in the same class, such as penicillin or cephalosporin, which has led to the development of a genetic system to attempt to enhance the production of erythromycin.