Query: NC_014215:1190447 Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1,
Lineage: Propionibacterium freudenreichii; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: Propionibacterium freudenreichii is a member of the "dairy propionibacteria", commonly isolated from cheese and other dairy products. Propionibacterium freudenreichii subsp. shermanii, formerly Propionibacterium shermanii, is important for the development of flavor and the characteristic holes in Swiss cheese. In addition, Propionibacterium freudenreichii subsp. shermanii has been used as a probiotic for humans and animals and may have a role in preventing of colon cancer.
Subject: NC_010162:3177324 Sorangium cellulosum 'So ce 56', complete genome
Lineage: Sorangium cellulosum; Sorangium; Polyangiaceae; Myxococcales; Proteobacteria; Bacteria
General Information: Sorangium cellulosum 'So ce 56' produces a large number of bioactive compounds, such as, the antifungal soraphen and the anticancer agent epothilone. This organism, like other myxobacteria, undergoes a complex development and differentiation pathway. When cell density increases, the organism switches to "social motility" where aggregates of cells can gather together into masses termed fruiting bodies that may consist of up to 100 000 cells. The motility system is not dependent on flagella like most bacteria, but instead relies on twitching pili: short extracellular appendages that may function analogously to oars in a rowboat. The myxobacteria have proved to be a rich source of novel natural products. Sorangium cellulosum produces a number of antibacterial, antifungal and cytotoxic substances which are being studies for therapeutic applications.