Query: NC_014212:319815 Meiothermus silvanus DSM 9946 chromosome, complete genome Lineage: Meiothermus silvanus; Meiothermus; Thermaceae; Thermales; Deinococcus-Thermus; Bacteria General Information: Isolation: Hot spring; Country: Portugal; Temp: Thermophile; Temp: 50C; Habitat: Hot spring. An aerobic, thermophilic, nonmotile Gram-negative bacterium isolated from the hot spring located at the end of a 450 m tunnel and from thermal water piped to a spa at Vizela in northern Portugal. M. silvanus is of special interest as it causes colored biofilms in the paper making industry and may thus be of economic importance as a biofouler. M. silvanus has also been detected in the gut of an invasive wood-boring beetle and in seawater adjacent to a Pacillopora meandrina coral colony at Palmyra Atoll.
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General Information: Lawsonia intracellularis PHE/MN1-00 was isolated from intestinal mucosal lesions in pigs that had proliferative enteropathy (PE). When introduced into health pigs, this organism produced the clinical and histological signs of PE. Causative agent for proliferative enteropathy in swine. This organism causes proliferative enteropathy (ileitis) in swine and other domesticated animals resulting in severe losses each year. This obligate intracellular pathogen infects the mucosa of the lower intestinal tract by initially infecting crypt cells, which are precursors that normally grow and divide in order to replace the epithelial cells. Once infection occurs, the crypt cells are stimulated to grow and divide abnormally, resulting in the proliferative phenotype. In severe cases of the disease the entire bowel can become affected and persist for up to 40 days, greatly affecting the host animal.