Query: NC_014169:2466442 Bifidobacterium longum subsp. longum JDM301 chromosome, complete Lineage: Bifidobacterium longum; Bifidobacterium; Bifidobacteriaceae; Bifidobacteriales; Actinobacteria; Bacteria General Information: Representatives of this genus naturally colonize the human gastrointestinal tract (GIT) and are important for establishing and maintaining homeostasis of the intestinal ecosystem to allow for normal digestion. Their presence has been associated with beneficial health effects, such as prevention of diarrhea, amelioration of lactose intolerance, or immunomodulation. The stabilizing effect on GIT microflora is attributed to the capacity of bifidobacteria to produce bacteriocins, which are bacteriostatic agents with a broad spectrum of action, and to their pH-reducing activity. Most of the ~30 known species of bifidobacteria have been isolated from the mammalian GIT, and some from the vaginal and oral cavity. All are obligate anaerobes belonging to the Actinomycetales, branch of Gram-positive bacteria with high GC content that also includes Corynebacteria, Mycobacteria, and Streptomycetes. This organism is found in adult humans and formula fed infants as a normal component of gut flora.
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General Information: This strain is a freshwater organism and is extensively studied due to its circadian clock which controls the expression of upwards of 800 genes during a 24 hour period. These unicellular cyanobacteria are also known as blue green algae and along with Prochlorococcus are responsible for a large part of the carbon fixation that occurs in marine environments. Synechococcus have a broader distribution in the ocean and are less abundant in oligotrophic (low nutrient) regions. These organism utilize photosystem I and II to capture light energy. They are highly adapted to marine environments and some strains have evolved unique motility systems in order to propel themselves towards areas that contain nitrogenous compounds. An obligate photoautotroph, it has been studied extensively by an international research community with respect to acquisition of organic carbon, transport and regulation of nitrogen compounds, adaptation to nutrient stresses, and reponse to light intensity.