Query: NC_014158:1479313 Tsukamurella paurometabola DSM 20162 chromosome, complete genome Lineage: Tsukamurella paurometabola; Tsukamurella; Tsukamurellaceae; Actinomycetales; Actinobacteria; Bacteria General Information: Isolation: Cases of systemic infection, usually in association with other diseases; Temp: Mesophile; Habitat: Sludge, Soil. Tsukamurella paurometabola, formerly Corynebacterium paurometabolum, was isolated from from mycetomes and ovaries of bed bugs (Cimex lectularius) and has also been found in soil and sludge. This organism has been isolated from cases of systemic infection, usually in association with other diseases.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: This strain is the first isolate of Ehrlichia chaffeensis, which was obtained from a patient on an army base in Arkansas, USA in 1990. Causes disease in humans. This organism is an obligate intracellular pathogen that exists within vacuoles in the cytoplasm of monocytes or granulocytes. Transferred during an insect (tick) bite, it can cause disease in humans (human monocytic ehrlichiosis) and can reside in several other animals and is a problem in immunocompromised patients. The bacterium inhibits phagosome-lysozome fusion as well as programmed cell death (apoptosis) of the host cell, similar to what is observed with Anaplasma phagocytophilum.