Query: NC_014158:1479313 Tsukamurella paurometabola DSM 20162 chromosome, complete genome
Lineage: Tsukamurella paurometabola; Tsukamurella; Tsukamurellaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: Isolation: Cases of systemic infection, usually in association with other diseases; Temp: Mesophile; Habitat: Sludge, Soil. Tsukamurella paurometabola, formerly Corynebacterium paurometabolum, was isolated from from mycetomes and ovaries of bed bugs (Cimex lectularius) and has also been found in soil and sludge. This organism has been isolated from cases of systemic infection, usually in association with other diseases.
Subject: NC_009142:6729512 Saccharopolyspora erythraea NRRL 2338, complete genome
Lineage: Saccharopolyspora erythraea; Saccharopolyspora; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: Source of the antibiotic erythromycin. Saccharopolyspora erythraea is the soil bacterium that produces the industrially important antibiotic erythromycin A. Erythromycin is a clinically important and potent macrolide antibiotic. It is used to treat infections caused by several prokaryotic pathogens such as Streptococcus, Staphylococcus, Mycoplasma, Ureaplasma, Chlamydia and Legionella. Production of this antibiotic is lower than others in the same class, such as penicillin or cephalosporin, which has led to the development of a genetic system to attempt to enhance the production of erythromycin.