Query: NC_014034:1507047 Rhodobacter capsulatus SB1003 chromosome, complete genome Lineage: Rhodobacter capsulatus; Rhodobacter; Rhodobacteraceae; Rhodobacterales; Proteobacteria; Bacteria General Information: This strain is a derivative strain isolated in the laboratory of Barry Marrs from the classical progenitor strain B10. It is rifampicin-resistant, produces GTA, and is capable of growing under high illumination (resistant to photooxidative killing). Bacteria belonging to the Rhodobacter group are metabolically versatile as they are able to use photosynthesis and usually can grow under both anaerobic and aerobic conditions. This organism is a facultatively phototrophic purple non-sulfur bacterium and the type species of the Rhodobacter group. The colony's color depends largely on the amount of oxygen present in its environment. While it is able to produce cellular energy in a number of different ways, it can rely on anoxygenic photosynthesis under anaerobic conditions in the presence of light. Some strains produce the Gene Transfer Element (GTA), a pro-phage particle capable of transferring genetic material between strains.
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General Information: This strain was isolated from a patient in 1994. Opportunistic pathogen that causes multiple hospital-acquired infections. This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.