Query: NC_014032:374426 Salinibacter ruber M8 chromosome, complete genome
Lineage: Salinibacter ruber; Salinibacter; Rhodothermaceae; Bacteroidetes Order II; Bacteroidetes; Bacteria
General Information: Salinibacter ruber (strain M8) is a brightly red-pigmented, motile, rod-shaped, extremely halophilic Gram-negative bacterium isolated from a saltern crystallizer pond in Mallorca, Spain. It grows optimally at salt concentrations between 20 and 30% and does not grow below 15% salt. S. ruber is among the most halophilic organisms known within the domain Bacteria. This organism is an extremely halophilic aerobe originally isolated from saltern crystallizer ponds in Spain. These bacteria can coexist in significant colonies with halophilic archaea under saline conditions. In contrast to other bacteria they do not regulate their intracellular salt conditions through proton pumps, but instead their protein makeup has adapted to be functional under high ionic conditions.
Subject: NC_010162:10208521 Sorangium cellulosum 'So ce 56', complete genome
Lineage: Sorangium cellulosum; Sorangium; Polyangiaceae; Myxococcales; Proteobacteria; Bacteria
General Information: Sorangium cellulosum 'So ce 56' produces a large number of bioactive compounds, such as, the antifungal soraphen and the anticancer agent epothilone. This organism, like other myxobacteria, undergoes a complex development and differentiation pathway. When cell density increases, the organism switches to "social motility" where aggregates of cells can gather together into masses termed fruiting bodies that may consist of up to 100 000 cells. The motility system is not dependent on flagella like most bacteria, but instead relies on twitching pili: short extracellular appendages that may function analogously to oars in a rowboat. The myxobacteria have proved to be a rich source of novel natural products. Sorangium cellulosum produces a number of antibacterial, antifungal and cytotoxic substances which are being studies for therapeutic applications.