Query: NC_014029:331919 Yersinia pestis Z176003 chromosome, complete genome Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria General Information: It was isolated from a dead marmot in Tibet Autonomous Region, China. Gram-negative straight rods, sometimes approaching a spherical shape. Y.pestis is always nonmotile. It is the causative agent of plague which is primarily a disease of wild rodents. Y.pestis is transmitted among wild rodents by fleas, in which the bacteria multiply and block the esophagus and the pharynx. The fleas regurgitate the bacteria when they take their next blood meal. Bacteria are transmitted subcutaneously to humans by the bite of infected fleas, but also by air, especially during pandemics of disease. Infective flea bites produce the typical bubonic form of plague in humans.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: This organism was discovered in 1819 by Bizio who named the organism after the Italian physicist Serrati. It was considered a nonpathogenic organism until late in the 20th century, although pathogenicity was noted as early as 1913. Serratia marcescens is an opportunistic human pathogen that is increasingly associated with life-threatening hospital-acquired infections. It is an environmental organism that has a broad host range, and is capable of infecting vertebrates and invertebrates, as well as plants. In humans, Serratia marcescens can cause meningitis (inflammation of the membrane surrounding the brain and spinal cord), endocarditis (inflammation of heart muscle) and pyelonephritis (inflammation of the kidneys). Many strains are resistant to multiple antibiotics. Environmental isolates are noted by production of the red pigment prodigiosin.